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Dermal fillers have become one of the most effective ways to restore lost volume, smooth wrinkles, and rejuvenate the skin without surgery. Among them, Radiesse stands out for its unique ability to do more than just fill — it helps your skin rebuild itself from within. By stimulating natural collagen production, Radiesse delivers results that last longer and look remarkably natural.
But despite its many benefits, Radiesse isn’t a one-size-fits-all treatment. Understanding what it can and can’t do is essential for achieving realistic, balanced, and long-lasting results.
At True Jewel Cosmetic Center, our experienced injectors use Radiesse to enhance facial structure, correct signs of aging, and restore youthful definition — all while maintaining a natural appearance. Here’s everything you need to know about how Radiesse works, what it treats best, and where its limits lie.
Radiesse is a biostimulatory dermal filler made from calcium hydroxylapatite (CaHA) microspheres suspended in a smooth gel. This formula not only replenishes lost volume instantly but also encourages the body to produce new collagen over time.
Unlike hyaluronic acid (HA) fillers, which simply add temporary plumpness, Radiesse provides structure and support that lasts. As the gel is absorbed, the CaHA particles continue to stimulate collagen production — creating natural firmness and elasticity that improves with time.
Because of its firm texture and long-lasting effects, Radiesse is often used for deeper lines, contouring, and areas that require strong structural support.
The treatment begins when a skilled injector places small amounts of Radiesse beneath the skin. The gel matrix provides immediate volume, smoothing out wrinkles and restoring youthful contours. Over the next several months, your body’s fibroblast cells respond to the calcium microspheres by generating new collagen fibers.
As the gel gradually dissolves, the newly formed collagen takes its place — leaving behind smoother, firmer, and more resilient skin. This process delivers both immediate and long-term rejuvenation, with results that can last up to 12–18 months, depending on your metabolism and the treated area.
In short, Radiesse works in two phases:
Radiesse is designed for deeper facial rejuvenation and contouring. It’s especially effective in areas where structure and firmness are needed rather than soft, delicate filling.
The deep lines that run from the sides of your nose to the corners of your mouth — known as nasolabial folds — often become more pronounced with age. Radiesse adds volume beneath these folds, softening their appearance and restoring balance to the midface.
Radiesse effectively fills marionette lines (the creases running from the mouth toward the chin) and enhances the lower face’s contour. It also helps lift sagging corners of the mouth, giving the face a more youthful, uplifted expression.
As collagen and fat diminish with age, the cheeks can lose their natural fullness, leading to a hollow or sunken look. Radiesse restores volume to the midface, subtly lifting and improving definition without the need for surgery.
One of Radiesse’s FDA-approved uses is for hand rejuvenation. With age, the skin on the back of the hands thins, exposing veins and tendons. Radiesse replenishes volume, creating smoother, more youthful-looking hands that match the face’s rejuvenated appearance.
Radiesse is an excellent option for defining the jawline. It provides structure and contour, subtly tightening the lower face for a refined, sculpted profile.
Horizontal lines or uneven texture on the chin can be softened with Radiesse, which provides durable support and a smoother skin surface.
Because of its firm texture, Radiesse can balance uneven areas of the face, subtly improving symmetry without overfilling or puffiness.
Unlike most fillers that last 6–12 months, Radiesse continues to stimulate collagen long after the gel has dissolved. Many patients enjoy results for up to 18 months or longer.
While Radiesse is powerful, it’s not suitable for every treatment area or cosmetic concern. Here are some limitations to keep in mind:
Radiesse is too dense for delicate areas like the lips or under-eyes. In these regions, softer hyaluronic acid fillers such as JUVÉDERM® or Restylane® are better choices.
Because Radiesse sits deeper in the skin, it’s best for structural enhancement rather than fine surface lines. Lighter fillers or skin treatments like microneedling and PRF are better for smoothing small creases or improving overall texture.
While Radiesse boosts collagen and reverses visible signs of aging, it doesn’t halt the natural aging process. Maintenance treatments are necessary to preserve results over time.
Unlike hyaluronic acid fillers, which can be dissolved with hyaluronidase, Radiesse can’t be reversed once injected. This makes it especially important to choose an experienced injector who understands facial anatomy and product placement.
Individuals with autoimmune conditions, bleeding disorders, or a history of severe allergies should avoid Radiesse. A consultation ensures the treatment is safe and suitable for your specific needs.
Both Radiesse and HA fillers restore facial volume, but they differ in texture, longevity, and function.
| Radiesse | Hyaluronic Acid (HA) Fillers | |
| Main Ingredient | Calcium hydroxylapatite microspheres | Hyaluronic acid gel |
| Consistency | Firm, supportive | Soft, flexible |
| Best For | Deeper wrinkles, jawline, cheeks, hands | Lips, under-eyes, fine lines |
| Longevity | 12–18 months | 6–12 months |
| Collagen Stimulation | Yes | Minimal |
| Reversibility | No | Yes (via hyaluronidase) |
Many patients benefit from a combination of both — using Radiesse for structure and HA fillers for softer detailing.
Your provider will review your goals, medical history, and facial anatomy to determine whether Radiesse is right for you. Each treatment plan is customized to achieve balanced, natural results.
Radiesse is injected using a fine needle or cannula. Most formulations include lidocaine for comfort, and the process typically takes 30–45 minutes. You may feel slight pressure as the filler is placed, but discomfort is minimal.
There’s no downtime. You may experience mild swelling, redness, or tenderness at the injection site, which subsides within a few days.
For best results:
Results appear immediately, with further improvement over the next few weeks as collagen production increases.
Radiesse offers some of the longest-lasting results among dermal fillers. Most patients enjoy visible improvement for a year or more, and some experience continued benefits beyond 18 months.
Longevity depends on factors such as metabolism, lifestyle, and the area treated. Annual touch-up sessions can help maintain results seamlessly.
You may be an excellent candidate for Radiesse if you:
Your provider will assess your unique facial structure to determine if Radiesse aligns with your rejuvenation goals.
Radiesse is one of the most advanced and versatile fillers available today — capable of restoring structure, lifting sagging features, and stimulating collagen for long-term rejuvenation. While it can’t address every cosmetic concern, its unique ability to rebuild skin from within makes it a standout choice for patients seeking natural, lasting results.
If you want to rejuvenate your face or hands without surgery, Radiesse can help you achieve smoother, firmer, and more youthful-looking skin that evolves beautifully over time.
Ready to discover what Radiesse can do for you? Schedule your consultation at True Jewel Cosmetic Center today. Our expert injectors will evaluate your skin, discuss your goals, and create a tailored treatment plan to help you achieve natural, long-lasting rejuvenation.
It’s ideal for the cheeks, chin, jawline, nasolabial folds, marionette lines, and hands.
Absolutely. Many patients combine it with HA fillers, Botox, or laser treatments for comprehensive rejuvenation.
People with bleeding disorders, autoimmune conditions, or active infections should avoid this treatment. It’s also not recommended during pregnancy or breastfeeding.
It depends on your treatment area and goals. Your provider will recommend the right amount during your consultation.
Our experienced injectors specialize in precision, artistry, and safety — delivering beautifully balanced results that enhance your natural features.

This November, True Jewel Cosmetic Center is offering exclusive member and non-member savings on Fillers, Botox, Microneedling, Morpheus8 and the C02 Cool Peel laser resurfacing treatment. Book now and save big this holiday season! Book now.
Whether you’re exploring injectables, skin rejuvenation, or body contouring — our board certified team is here to help you look and feel your best. Reveal your true beauty today.
Free consultations offered.
10601 Washington Blvd #107a
Culver City, CA 90232
Sunday: 9:30 AM–4 PM
Monday: 9:30 AM–4 PM
Tuesday: 9:30 AM–6 PM
Wednesday: 9:30 AM–6 PM
Thursday: 9:30 AM–4 PM
Friday: 9:30 AM–4 PM
Saturday: Closed
This November, True Jewel Cosmetic Center is offering exclusive member and non-member savings on Fillers, Botox, Microneedling, Morpheus8 and the C02 Cool Peel laser resurfacing treatment. Book now and save big this holiday season! Book now.