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The Science Behind Exosomes and How Do They Work

How you look determines your mood for the day! It’s no surprise that people are seeking ways to make their lives better. Despite the many options available to achieve it, sometimes the best ones are the simplest methods.

Exosomes are tiny vesicles released from cells. They are detected in the bloodstream and have been shown to play a major role in many health conditions, for instance, breast cancer.

This article will cover what exosomes are, how they work, and how they can improve your life.

So, What Are Exosomes?

The word “exosome” comes from the Greek meaning “outside” or “outer shell.” It refers to a small vesicle (a tiny sac) released by cells.

Exosomes are tiny, protein-coated bubbles. They exist in bodily fluids, such as blood and urine. Recently, they have been shown to play a role in regenerative medicine; however, what exactly do they do?

Regenerative medicine is the science of using stem cells to repair and replace damaged tissues or organs to improve/restore function. It aims to harness the body’s own repair mechanisms to restore normal anatomy and physiology.

As the name suggests, exosomes are released from cells into the surrounding environment. They consisted of membranes and a small amount of genetic material (RNA). Due to their tiny sizes (around 100 nanometers), it’s easy for them to pass through cell membranes and into other cells.

This characteristic makes them ideal for carrying information between cells, for instance, between bone marrow stem cells and their neighboring cells. Therefore, in regenerative medicine research, scientists are using exosomes to deliver therapeutic molecules like proteins or drugs into other tissues.

For instance, researchers have developed methods of isolating stem cell-derived exosomes from blood samples taken from patients with cardiac disease. These exosomes are then used as vehicles to deliver therapeutic proteins that promote cardiac repair to damaged heart tissue.

How Do They Work?

Exosomes are like little messengers. They carry information from one cell to another, across the walls of blood vessels, and into other tissues.

When an exosome reaches its destination cell, these molecules allow it to dock with the cell and merge with it. Therefore, it can deliver whatever cargo it contains. This could be DNA or RNA needed for growth or repair processes within that particular cell type.

Exosomes also help regulate how healthy cells grow. For example, when you’re pregnant, some exosomes from your placenta travel up your body to help your baby grow big enough for birth. In addition, they control how fast those little babies learn new things after they’re born. Thus affecting their behavioral characteristics later on in life.

What Cosmetic and Medical Treatments Are Exosomes Applied

Exosomes have shown potential for treating a variety of cosmetic and medical conditions. Some examples include the following:

Cosmetic treatments:

1. Skin Rejuvenation

Exosomes stimulate the production of elastin and collagen. Two proteins are essential for maintaining the structure and elasticity of the skin. As we age, their production slows down, causing our skin to start losing its elasticity. Thankfully, exosome applications prevent that from happening.

When used with other injectable fillers, exosome-based products help to restore volume loss, enhance skin tone and texture, and lessen the appearance of wrinkles.

2. Acne Treatment

Acne is a common skin infection that affects around 50 million Americans annually. Exosomes can be applied topically to help prevent new breakouts from forming on your face or body.

They also help lessen existing acne by reducing inflammation and killing bacteria on the surface of your skin. It helps prevent future breakouts as well as treat existing ones faster than traditional treatments like antibiotics.

3. Hair Growth

Exosomes can be applied directly to an area of thinning hair in order to stimulate new growth. If you’re balding in one spot, exosome applications could help “bring it back” in the area by promoting new hair growth!

It is helpful for those who have lost their eyebrows and eyelashes due to chemotherapy treatments for cancer since exosomes can be used to regrow those as well.

Medical Treatments:

1. Osteoarthritis

Osteoarthritis is a degenerative disease that causes pain and stiff joints. The condition is common in middle-aged and older adults. However, anyone can develop it. Exosomes treat osteoarthritis by reducing inflammation and enhancing bone repair in the knee joint.

2. Cancer Treatment

Exosomes for cancer cells are used as new treatments for cancer since they can be injected directly into the bloodstream. The advantage of exosomal injections is that they deliver therapeutic proteins directly into the bloodstream at a lower cost than traditional treatments like chemotherapy or radiation therapy. These methods require expensive equipment and involve significant risks of side effects.

3. Chronic Pain

Chronic pain is challenging to treat because it is often associated with neuropathic pain. Exosomes are used as part of treatment for chronic pain because they prevent neuropathic pain from developing after injury to the spinal cord or nerve roots in rats.

4. Autoimmune Diseases

Exosomes from stem cells can be used to treat autoimmune illnesses. These diseases result when the immune system attacks healthy tissues instead of fighting off infections.

Therefore, exosomes from stem cells treat autoimmune diseases by reducing inflammation and stimulating immune tolerance to specific antigens.

5. Wound Healing

Exosomes are useful in wound healing due to their ability to induce angiogenesis or the formation of new blood vessels. They help with tissue regeneration by transporting growth factors from stem cells to the damaged area.

This promotes tissue repair and regeneration. In this way, exosomes can be used as a treatment for damaged skin or other organs.

6. Cardiovascular Diseases

Exosomes are used to treat cardiovascular disease by preventing atherosclerotic plaques from forming in blood vessels. In addition, it treats existing plaques that have formed within blood vessels. It does this by breaking them down into smaller pieces that can be removed by macrophages (cells that engulf foreign matter).

This prevents further damage from occurring due to clogged arteries and allows for more efficient blood flow throughout the body.

7. Neurodegenerative disorders

In Parkinson’s disease, exosomes are released by neurons into the blood. The exosomes contain alpha-synuclein, which can damage neurons in the substantia nigra. Exosomes have been shown to increase in patients with Alzheimer’s disease and other neurodegenerative disorders.

Who Can Undergo Exosome Therapy?

Exosome therapy is a type of treatment that harnesses the power of exosomes. However, not all can undergo this treatment, as the reasons depend on what your expert says. As a result, some of the individuals who can undergo the treatment are those who are:

  • Fighting cancer cells
  • Want to Improve memory by stimulating stem cell activity in the brain
  • Boosting the immune system
  • Repairing damaged heart tissue after a heart attack or injury
  • Chronic kidney disease (CKD)
  • Those who want to improve their overall body look

Expected Results from Exosomes Treatment

After this treatment, expect the following changes.

  • Improvement in your tissue repair and regeneration. Exosomes improve tissue repair and regeneration by enhancing the body’s natural ability to heal itself.
  • Reduced inflammation and pain. This protein reduces inflammation and pain by reducing the production of inflammatory cytokines (proteins that cause inflammation in the body.)
  • Enhanced your immune function. Exosomes increase the number of T-cells in your body, which help fight off cancer cells and infections.
  • Improvement in your skin texture and appearance. Exosomes are able to penetrate the skin and deliver their cargo of growth factors. These are proteins and other compounds that help promote healthier, more youthful-looking skin.
  • Improved your joint function and mobility. They can help reduce inflammation in joints, making them less painful and improving mobility.
  • Reduced scar tissue formation. Exosomes are able to deliver a variety of growth factors that can reduce scar tissue formation by up to 50 percent in some cases.
  • Experience improved hair growth and thickness. Exosomes can deliver growth factors that increase blood flow to the scalp, which helps promote hair growth and thickness.

What Next? Contact True Jewel in Culver City, CA, for Your Body Care

Do you need noninvasive treatment? Exosomes are a type of non-surgical treatment used to aid in reducing wrinkles, improving skin tone and texture, and reducing the appearance of scars. They can be used to help rejuvenate the overall look and feel of your skin again. But who’s your trusted and expert spa in Culver City?

True Jewel Cosmetic Center is the answer! We are a full-service Medical Spa in Culver City, CA, offering a variety of services to meet your cosmetic enhancement needs. Our experienced staff will provide you with the most advanced treatments and procedures available.

Our team of board-certified plastic surgeons, registered nurses, and licensed estheticians are dedicated to serving you with the latest in cosmetic surgery and medical spa treatments. 

We offer many noninvasive procedures as well as surgical options to help you look younger. Get started today by contacting True Jewel Cosmetics Center today. Know what you need through our easy consultation procedure before the main service.

Book An Appointment

Do you live in or near Culver City, Venice, Playa Vista, or Marina Del Ray and are you ready to book your future appointment for a exosomes treatment? Click below! Free consultations.

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